Interim analysis of the Robo-G study

Prof Dr Lore Decoster discusses the Interim analysis of the Robo-G study which investigates the feasibility and functional outcomes of robotic surgery in older patients with newly diagnosed colorectal cancer.

The Robo-G study is a prospective observational study including patients aged 70 years or older with colorectal cancer who are eligible for robotic surgical treatment. Participants are followed for a period of one year and undergo repeated comprehensive geriatric assessments. At baseline, prior to surgery, patients are evaluated with respect to functional status, mood, nutritional status, and quality of life. Functional status is assessed using activities of daily living (ADL), instrumental activities of daily living (IADL), grip strength, and the Timed Up and Go test.

Follow-up assessments are conducted at 3 months, 6 months, and 12 months after surgery to evaluate postoperative evolution and recovery. The poster presented focuses specifically on functional outcomes over time. Results indicate that the majority of patients maintain stable functional status following robotic surgery. Stability is observed across basic and instrumental daily functioning, as well as objective physical performance measures such as grip strength and mobility.

Although a subset of patients demonstrates a transient decline in function at 3 or 6 months postoperatively, most exhibit functional recovery by one year after surgery. Overall, these findings suggest that robotic surgery is a feasible and well-tolerated treatment option for older patients with colorectal cancer. Ongoing follow-up aims to further elucidate long-term functional trajectories in this population.