Integrative Neuro-Cognitive Remediation Therapy for cancer survivors with cognitive problems

Dr Nathalie Van Laer is a psychologist and PhD student at UZ Brussel. Her poster presents an observational study evaluating Integrative Neurocognitive Remediation Therapy for Cancer Survivors, a multidisciplinary intervention designed for individuals who experience persistent cognitive difficulties after completing cancer treatment. Such difficulties—including problems with concentration, memory, and complex daily activities—can substantially impair quality of life and functional independence.

The program takes place at the Centre Hospitalier Universitaire Brugmann in Brussels under supervision of prof dr Anne Rogiers, head of the Department of Psychiatry. It consists of full-day group sessions held once per week and integrates multiple therapeutic components. These include psychoeducation, cognitive behavioural therapy, acceptance and commitment therapy, neurocognitive strategy training, functional skills training, and adaptive physiotherapy. This structure allows for a comprehensive approach targeting cognitive, psychological, and physical contributors to post-treatment cognitive impairment.

Thirty-eight cancer survivors completed the program and underwent evaluations at baseline, immediately after the intervention, and again at six-month follow-up. At each time point, participants received a neuropsychological assessment, completed psychometric questionnaires, and were evaluated on daily functioning. The results demonstrated significant improvements in both objective neuropsychological performance and self-reported cognitive functioning, observed directly after the intervention and maintained at six months. Participants also reported reduced psychological distress at follow-up, along with a numerical reduction in fatigue levels.

Importantly, all participants showed meaningful improvements in daily functioning, including tasks such as reading, household activities, and engaging in conversations—areas often affected by cognitive impairments following cancer therapy. These gains were sustained or further enhanced at the six-month assessment.

Overall, the findings indicate that this integrative, multidisciplinary program is effective in improving cognitive outcomes, reducing psychological distress, and enhancing daily functioning in cancer survivors, with benefits that persist over time.