A dual role for PSIP1 in T-ALL
T-cell acute lymphoblastic leukemia (T-ALL) is an aggresive hematologic malignancy that accurs for 10-15% of pediatric and 25 of adult ALL cases. Identification of key drivers and pathways in T-ALL is therefor crucial in the development of targeted therapeutic strategies. With this study, the team for prof. Pieter Van Vlierberghe of UGent identifies the role of PSOP1 in the initiation and maintenance of T-ALL, by analyzing the effects caused by PSIP1 loss, both in mice models and human T-ALL cell lines.
With the educational support of:
