Predictive value of D-dimer concentrations in patients on long-term direct oral anticoagulation after a venous thrombo-embolism

During the 2024 annual ASH meeting, Prof Cédric Hermans, head of the haematology department at the Cliniques Universitaires St.-Luc in Brussels, shared the results of an analysis looking into the levels and predictive potential of D-Dimers in patients on long-term anticoagulation with a direct oral anticoagulant for a venous thrombo-embolism (VTE). During secondary VTE prevention, the levels of D-Dimer were generally low and did not predict for a VTE recurrence. The age-adjusted D-dimer levels were somewhat higher in men with gonosomal aneuploidy and in patients with a deep vein thrombosis complicated by post-thrombotic syndrome.